Antibacterial Activity of Aqueous Plant Extracts and Honey against UTI causing Superbugs

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Muhammad Sohail et. al

Abstract

The fluent and unprescribed use of drugs has created an alarming situation of drug resistance acquired by pathogenic microorganisms. In (Urinary tract infections) UTI choice of drug is limited and increasing resistance against available antibacterial drugs made it worse than other infections. In present study urine samples from people suffering from urinary tract infections (UTI) were taken and tested for presence of highly drug resistant microorganisms by performing antibiotic susceptibility test. Out of thirty bacterial pathogens five were selected for molecular characterization and antimicrobial sensitivity testing against plant extracts. Knowing the fact that Kalonji, Methi, Neem, Jaifal and honey have great pharmaceutical potential and medical importance without any side effect, their crude extracts were used in well plate assay to determine the antibacterial activity against the UTI causing organisms. Plant extracts and honey showed remarkable antimicrobial activity against drug resistance pathogens.   Another important aspect of this research is the fact that Pakistan is a developing country and most people cannot afford expensive third or fourth generation drug treatment. This scenario demands the discovery of new pharmaceutical drugs that can cope with the drug resistance problems by effectively eliminating pathogenic UTI causing organisms without causing any side effects in patients suffering from UTI. 

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